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ea0094p54 | Metabolism, Obesity and Diabetes | SFEBES2023

Unveiling the metabolic benefits of GLP-1 analogues in alström syndrome: implications for monogenic syndromic obesity management

Ali Sadaf , Paisey Richard , da Silva Xavier Gabriela , Hiwot Tarekegn

Background: Glucagon-like-peptide-1 (GLP-1) has been shown to improve body weight and glycaemic control in patients with common obesity and type 2 diabetes. Whether it confers the same metabolic benefits in monogenic syndromic obesity is unknown. This observational study aimed to examine the real-world efficacy of GLP-1 analogues in Alström syndrome (ALMS), a form of monogenic obesity.Method: We screened all 72 UK a...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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